Advances in Cell & Stem Cell Research Congress

Biography:

Abstract:

Glycation reaction is the major cause of aging. The enhanced generation and accumulation of Advanced Glycation End Products (AGEs) from glycation reaction can cause the proteins become cross-linked, have been linked to increased risk for micro vascular and micro-vascular complications associated with diabetes mellitus, neurodegenerative diseases, inflammatory diseases, autoimmune diseases, cancer and aging. De-glycating molecule or AGE-crosslinks breaking molecule can break down crosslinking of proteins in human body that lead to pathophysiological mechanism has been recognized as a causative factor in diabetic complications, age-related diseases as nephropathy, retinopathy, elderly impaired macro and micro vascular-related diseases, Alzheimer disease and skin aging. In our study, we summarized results of de-glycating molecule or AGE-crosslinks breaking molecule application with 14 patients in anti-aging and integrative medicine clinic, having risk of metabolic syndromes as diabetes, dyslipidemia, hyperthyroid and skin aging. After regular intake of de-glycating molecule or AGE-crosslinks breaking molecule with loading dose 24,800 de-glycating unit for 2 weeks and maintenance dose 12,400 de-glycating unit continuously for 6 months. There are significant result of well controlled parameter of blood chemistry profile in diabetes, dyslipidemia and hyperthyroid as blood sugar, Hb a1c, cholesterol, triglyceride, HDL, LDL, T3 and TSH. There are good satisfaction result in skin aging as improve skin elasticity and brown spots. Moreover, there are good results of improvement in general health as good sleep, good recovery after exercise, better joints movement and improved sexual function. De-glycating molecule or AGE-crosslinks breaking molecule can be the application in anti-aging practice for longevity, particularly in patients who are risk or having metabolic syndrome.