The track category is the heading under which your abstract will be reviewed and later published in the conference printed matters if accepted. During the submission process, you will be asked to select one track category for your abstract.
Stem cells are defined as precursor cells that have the capability to self-renew and to come up with multiple mature cell types. Stem cells are an ongoing source of the differentiated cells that make up the tissues and organs of plants and animals. After collecting and culturing tissues is it possible to classify cells as per their operational concept. There are 2 major types of stem cells: Embryonic Stem Cells and Adult Stem Cells that is also known as tissue stem cells. This difficulty in characteristic stem cells in situ, without any manipulation, limits the understanding of their true nature. There is great interest in stem cells as a result of they have potential in the development of therapies for replacing defective or damaged cells ensuing from a variety of disorders and injuries, like Parkinson disease, heart disease, and diabetes.
Hematopoietic Stem Cells are the immature cell that is developed into all types of blood cells, including red blood cells, white blood cells, and platelets which are found in the peripheral blood and the bone marrow. These stem cells are also called blood stem cell. Studies have described two populations of Hematopoietic Stem Cells that are Long Term and Short Term. Long-Term Hematopoietic stem cells which are capable of self-renewal, while Short Term Hematopoietic stem cells do not have this capacity.
Embryonic Stem Cells are developed when embryos formed during the blastocyst phase of embryological development. They can grow in all derivatives of the 3 primary germ layers i.e. ectoderm, endoderm and mesoderm. These include each of the more than 220 cell varieties within the adult body. Pluripotency distinguishes embryonic stem cells from adult stem cells found in adults; whereas embryonic stem cells can generate all cell types within the body, adult stem cells are multipotent and can produce only a restricted number of cell types. Embryonic stem cells are capable of propagating themselves indefinitely. This allows embryonic stem cells to be employed as useful tools for both research and regenerative medicine, because they can produce limitless numbers of themselves for continued research or clinical use.
Induced Pluripotent Stem Cells (iPSCs) are the adult stem cells derived from skin or blood cells which are reprogrammed to an embryonic stem cell maintaining the essential properties of introducing important genes and also to enables the development of an unlimited source of any type of human cell needed for the therapeutic purpose. Researchers have rapidly developed the techniques for generating iPSCs and by creating a new and powerful way to "de-differentiate" cells whose developmental fates.
Though the concept of stem cell niche was prevailing in vertebrates, the first characterization of stem cell niche in vivo was figured out in drosophila germinal development. A stem-cell niche is an area of a tissue that provides a specific microenvironment, in which stem cells are present in an undifferentiated and self-renewable state. Cells of the stem-cell niche interact with the stem cells to take care of them or promote their differentiation. Characterization of these stem cell niches depends on the ability to identify stem cells in vivo in their normal setting. Through comparison of different stem cell systems, some themes emerge that indicate possible general characteristics of the relationship between stem cells and their supporting niche.
Stem cell banking is the extraction, processing and storage of stem cells which can used for treatment when required. Stem cells have the amazing power to transform into any tissue or organ in the body. It is due to this unique characteristic that they have the potential to treat over 80 life threatening diseases, and provide numerous benefits to the baby, its siblings and the family. There are variety of sources from where stem cells can be banked, with the most common amongst them being the umbilical cord. Cord blood banking is that the extraction of stem cells from the umbilical cord. This is done during childbirth and is a fast, hassle free and painless procedure. While, the umbilical cord and cord blood are the foremost common sources of stem cells - the Placenta, amniotic sac and amniotic fluid are by far the richest sources, in terms of both - quantity and quality. Some other rich sources of stem cells are Placenta, Umbilical Cord, Amniotic Fluid, Dental Stem Cells, Menstrual Fluid, Adipose Tissue and Bone Marrow.
A procedure in which a patient receives healthy blood-forming cells (stem cells) to replace their own, when stem cells or bone marrow are damaged or destroyed by disease, as well as some types of cancer, or by high doses of chemotherapy or radiation therapy used to treat cancer. The healthy stem cells may come from the blood or from a donor’s bone marrow or from the umbilical cord blood of a newborn baby. A stem cell transplant may be autologous (use of stem cells from your own bone marrow or blood), allogeneic use of stem cells from someone else, the donor could also be a relative or somebody who isn't associated with you) or syngeneic (use of stem cells from an identical twin). The stem cells within the bone marrow transform into red blood cells, white blood cells and platelets. when these blood cells mature, they go into the peripheral blood (the blood that flows through the body). If the bone marrow is damaged or destroyed, it can’t create normal blood cells. in a stem cell transplant, healthy stem cells are placed in your body to assist your bone marrow start to work properly. The new stem cells make healthy blood cells.
Stem Cell Therapy is the treatment for various disorders which non-seriously life-threatening by using stem cells. These stem cells can be obtained from a lot of different sources and used to potentially treat more than 80 disorders which include neuromuscular, organ, chronic and degenerative disorders. Chronic disorders arise from degeneration or wear and tear of cartilage, muscle, bone, fat or the opposite organ, tissue or cell. This may occur owing to a spread of reasons, but it's usually the tactic spoken as aging, or 'getting old' that is the largest cause. Stem cell therapy is currently being researched for the treatment of various diseases. While research and clinical trials are in process with varying degrees of success, stem cell therapy holds the potential to offer a successful cure for these conditions.
Cancer is defined as the abnormal growth of cells that possesses the ability to spread to other cells and tissues. Cancer is one of the major illness which it seemed to be more prevalent all over the world. Even though the death rate and peoples suffering from these diseases are in greater number in recent years. There are over 200 variety of types of cancer across the globe. The death rate increasing year-by-year due to this disease even in developed countries. Cancer Stem Cells (CSCs) are a small population of cells inside tumors with capabilities of self-renewal, differentiation, and tumorigenicity once transplanted into an animal host. The CSC hypothesis thus doesn't imply that cancer is always caused by stem cells or that the potential application of stem cells to treat conditions like cardiovascular disease or diabetes which is able to result in tumor formation. Rather, tumor-initiating cells possess stem-like characteristics to a degree sufficient to warrant the comparison with stem cells along with the observed experimental and clinical behaviors of metastatic cancer cells are extremely resembling the classical properties of stem cells
As an organism grows and develops, carefully orchestrated chemical reactions activate and deactivate components of the genome at strategic times and in specific locations. Epigenetics is that the study of these chemical reactions and the factors that influence them. It is strongly believed that there are some signals at the epigenetic level that regulate the fate of the stem cells. Though all of the cells in our body contain the same genetic makeup. These genes are not necessarily active at all times, rather they are expressed at times when needed in a highly controlled fashion.
Tissue Engineering is a scientific field centered on the advance of Tissue and Organ Substitutes by controlling their environment, biomechanical and biophysical parameters which include the utilization of a different or same scaffold for the arrangement of new tissue. These frameworks empower the In-vitro investigation of human physiology and physiopathology, while giving a rendezvous of biomedical instruments with potential materialness in toxicology, medicinal gadgets, tissue substitution, repair and Regenerative Medicine. Regeneration is that the progression of renewal, regeneration, and growth that makes it cells, organ regeneration to natural changes or events that cause damage or disturbance. This study is carried out as craniofacial tissue engineering, in-situ tissue regeneration, adipose-derived stem cells for tissue science which is also a breakthrough in cell culture technology. The study isn't stopped with the regeneration of tissue wherever it is further carried out in relation to cell signaling, morphogenetic proteins. Most of the neurological disorders occurred accidentally having a scope of recovery by replacement or repair of intervertebral discs repair, spinal fusion and plenty of more advancement.
Regeneration Medicine is that the Survival of any living body essentially relying upon its capability to repair and recover injured or harmed tissues or potential organs amid its lifespan following injury, illness, or maturing. This will shape the system for recognizing novel clinical medicines which will enhance the mending and regenerative limit of individuals. The Regeneration process involves Cell Proliferation where most of the medical disorders occurred accidentally includes a scope of recovery by replacement or repair of intervertebral discs repair, spinal fusion and plenty of more advancements.
Cell reprogramming is the process of reverting mature, specialized cells into induced pluripotent stem cells. Reprogramming also refers to the erasure and re-establishment of epigenetic marks during mammalian germ cell development. The discovery of Induced pluripotent stem cells emphasizes on reprograming of any adult differentiated cells into stem cells by genetic modification under precisely controlled laboratory conditions. Reprograming of cells is supposed to presage revolution in both, medical and biological research and allows modeling and analysis of human diseases and cell cytotoxicity by drugs. The technique is still in its growing phase and requires a great deal of extensive research and approval from authorities for further trials.
Stem cell nanotechnology has emerged as a brand-new exciting field. Experimental and theoretical studies of interaction between nanostructures or nanomaterials and stem cells have made great advances. The importance of nanomaterials, nanostructures, and nanotechnology to the basic developments in stem cells-based therapies for injuries and degenerative diseases has been recognized. Apart from tracking the localization of stem cells, nanotechnology has improved targetability, half-life, and stability of stem cells by providing a suitable microenvironment. In particular nanomaterials have played a significant role in the isolation and proliferation or differentiation of stem cells and intracellular delivery of small and macromolecules within stem cells. In this field over the past few years, explore the application prospects, and discuss the issues, approaches and challenges, with the aim of rising application of nanotechnology in the stem cells research and development.
Stem Cell Technologies will become a global biotechnology that manufactures, develops and sells product by providing the services to support academic and industrial scientists. Stem cells analysis and development team typically collaborates with educational institutes and industrial partners to manufacture, develop and distribute a specific product for a given analysis. A stem cell has helped several scientific communities and industries to develop technologies to achieving the world biotechnology market. The corporate makes a specialist in developing cell culture media, cell separation product, instruments and completely different reagents to be utilized in the cell, immunology, cancer, Regenerative medicine and cellular treatment analysis.
There are many research advancements and applications and of Stem Cells. Stem cell research that can be applied to develop new therapies includes cell replacement therapy, development of drugs, using iPSC technology to generate stem cells from the patient’s skin or blood, using trans differentiation technology to convert a specialized cell type to a progenitor cell and many more. It also carries the immense potential for treating a number of human diseases such as to repair or regenerate blood vessels, treatment of eyesight, Diabetes, Neurodegenerative Disorders and Wound Healing etc.
Carefully planned and ethically approved clinical trials resulting from a robust preclinical pathway are necessary to advance the field. This will require a programmatic approach that involves partnerships of clinicians, academics, industry, and regulatory authorities with a focus on understanding basic biology that informs a tight linkage between preclinical and clinical studies. Rather than suggesting that clinical trials are premature, such trials should be encouraged as part of multidisciplinary programs in regenerative medicine.
The field of bioethics has addressed a broad swathe of human inquiry, ranging from debates over the boundaries of life, surrogacy, and the allocation of scarce health care resources to the right to refuse medical care for religious or cultural reasons. StemGen is a research database of international, regional and national normative instruments concerning the socio-ethical and legal aspects of stem cell research and related therapies. The regulation of stem cell research is an issue that has drawn much comment, criticism and even judicial arbitration in recent years along with the marketing status of Stem Cells, Cell therapy, Regenerative Medicine, Tissue Engineering and many more worldwide.